Both the Tuskegee study and the Willowbrook study produced research data that was beneficial to advancing medical science. Is the use of the data from these and other such experiments ethically defensible?

Both the Tuskegee study and the Willowbrook study produced research data that was beneficial to advancing medical science. Is the use of the data from these and other such experiments ethically defensible? Why or Why Not? In composing your response, include the justifications for your position using one or more ethical theories (theories are listed below).
Would the ethical deficiencies in the Tuskegee Study have been eliminated had the men been informed that they were part of a research study that would provide them no direct benefit, but they would be financially compensated? Why or Why Not? Remember to justify your response.