- Define genome:
- What is the difference between DNA in the chromatin form and the chromosome form? What form is DNA in during most of the cell cycle?
- What is the difference between the centromere and the kinetochore?
- What happens during each of these phases of the cell cycle?
G1:
S:
G2:
M:
- The mitotic spindle is mainly made of what type of protein fiber?
- How does cytokinesis differ between plant and animal cells?
- Is binary fission truly mitosis? What type of organisms use binary fission for reproduction? Is this process sexual or asexual?
- Draw/depict the phases of mitosis from prophase to the end of cytokinesis for an animal cell containing a total of six chromosomes.
- What is the cell cycle control system and why is it important?
- What happens to most mammal cells when they reach the G1 checkpoint?
- Explain how MPF helps to regulate the cell cycle. (See Fig 12.16)
- What is a growth factor? Provide an example from the chapter.
- What does cancer have to do with the cell cycle?
- Explain why each of the following would undergo mitosis:
An early embryo:
An amoeba:
Skin cells:
A broken bone:
- How is prokaryotic DNA different from eukaryotic DNA?
- Are the daughter cells produced by mitosis clones of the parent cell?
- When mitosis is used for reproduction, is it sexual or asexual? What type(s) of organisms use mitosis for reproduction?
CHAPTER 13: MEIOSIS & SEXUAL LIFE CYCLES
- Define:
Gene
Allele
Locus
Gametes
Somatic cells
- What is the difference between sexual and asexual reproduction (in terms of number of parents, and variation in offspring)?
- What is the difference between homologous chromosomes and sister chromatids? (Where do they “come from”? Are they identical?)
- What are autosomes? How many pairs of autosomes do humans have?
- Meiosis produces gametes.
What are gametes used for?
What is the union of gametes called?
The union of gametes creates what?
- What is the difference between cells that are haploid and cells that are diploid?
Are gametes haploid or diploid?
Are somatic cells haploid or diploid?
- Do the following eukaryotes primarily reproduce sexually or asexually?
Animals:
Plants:
Fungi:
- How many daughter cells does meiosis produce?
Are they diploid or haploid?
Are they clones of the parent cell?
- Draw/depict Meiosis Prophase I and Metaphase I for three pairs of chromosomes:
- What happens during synapsis? Does synapsis happen during mitosis?
- What are three things that happen during meiosis but not mitosis? (See P.260)
- What is independent assortment of chromosomes? During which phase of meiosis does this occur?
- If a cell undergoing meiosis has a haploid number of 6, what is the number of different combinations of chromosomes that can occur in the daughter cells?
- Explain what crossing over is and how it increases genetic variation in sexually reproducing organisms.
- How is genetic variation introduced into asexually reproducing organisms like bacteria?
- Why do most eukaryotes reproduce sexually? (What is the advantage?)
CHAPTER 14: MENDEL & THE GENE IDEA
- What is the difference between a character and a trait?
- What is the difference between an individual’s genotype and phenotype?
- What do we know about the genotype of true-breeding plants in Mendel’s experiments?
- In Mendel’s experiments, what is the genotype of the individuals in a monohybrid cross (F1 x F1)? What is their phenotype?
- Are dominant alleles always more common than recessive alleles in a population?
- What is the law of segregation? This occurs during which phase of meiosis?
- In complete dominance, do homozygous dominant individuals have the same phenotype as heterozygous individuals? Do they have the same genotype?
- Mrs. Smith has a widow’s peak (her genotype is Ww), but her husband does not (his genotype is ww).
What are the possible gametes for Mrs. Smith ___________ Mr. Smith _____________
Make a Punnett Square for potential offspring produced by this couple:
What is the probability that their child will have a widow’s peak?
What is the probability that they will have two children both with widow’s peaks?
- Mendel’s dihybrid cross (F1 x F1) looked at the inheritance of two characters. What were the genotypes of the F1 plants?
Did he find that seed color and seed texture were inherited together or independently? Explain.
- Besides having a widow’s peak (Ww), Mrs. Smith also has attached earlobes (ff). Mr. Smith does not have a widow’s peak (ww) or attached earlobes (Ff).
Considering both of these characters together, what are the possible gametes
for Mrs. Smith _________________________ and Mr. Smith __________________________?
Make a Punnett Square for both of these characters together.
What is the probability that their child will have a widow’s peak and attached earlobes?
What is the probability that their child will have no widow’s peak NOR attached earlobes?
- An individual has a genotype WwFf. What are the possible gametes that this person can make in respect to these two genes?
- In incomplete dominance, do homozygous dominant individuals have the same phenotype as heterozygous individuals?
- How is codominance different from incomplete dominance?
- Do most genes only have two alleles?
- Explain:
Pleiotropy
Epistasis
Polygenic inheritance
- Give an example of how environment can affect an organism’s phenotype?
- In a recessively-inherited disorder, what are the genotypes of:
A normal person
A carrier
An afflicted person
- Why are dominantly-inherited disorders less common than recessively-inherited disorders?
- Duncan and Maria are both carriers of cystic fibrosis, a recessively-inherited disorder. Draw a Punnett square to show their possible offspring.
What is the probability that their child will have cystic fibrosis?
CHAPTER 15: CHROMOSOMAL BASIS OF INHERITANCE
- According to Morgan’s terminology, what is the difference between wild type and mutant phenotype?
- Look at Figure 15.4. How did Morgan figure out that the gene for eye color is on the X chromosome? Explain the F1 cross and what was produced in F2.
- What are sex-linked genes?
- In mammals (and fruit flies) are males or females the heterogametic sex? Is this the case for all species?
- Draw a Punnett square to show how sex is determined in humans (XX x XY). This also explains why we have about a 50:50 sex ratio.
- Which chromosome carries more genes, X or Y?
Are there genes on the Y chromosome that are important for all humans? What type of genes are found on the Y chromosome?
- Why are men more likely than women to get a sex-linked disorder?
- Can a man pass on a sex-linked disorder to his sons? Explain.
- Define:
Non-disjunction
When can non-disjunction occur?
Aneuploidy
- When aneuploidy occurs, what usually happens to the embryo?
- Explain what happens to the DNA when the following occur:
Deletion
Duplication
Inversion
Translocation
- What causes Down syndrome?